reviewHealthcareJul 5, 2023GOLD OA

Antimicrobial Resistance: A Growing Serious Threat for Global Public Health

International Islamic University Malaysia · Purdue University West Lafayette · +7 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Antibiotics are among the most important discoveries of the 20th century, having saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from increasing use and misuse of antibiotics over the years. The transmission and acquisition of AMR occur primarily via a human-human interface both within and outside of healthcare facilities. A huge number of interdependent factors related to healthcare and agriculture govern the development of AMR through various drug-resistance mechanisms. The emergence and spread of AMR from the unrestricted use of antimicrobials in livestock feed has been a major contributing factor.…

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