MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies

Abstract As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in cancer development. Since the discovery of the identity and clinical functions of miRNAs, over the past few decades, the roles of miRNAs in cancer have been actively investigated. Numerous pieces of evidence indicate that miRNAs are pivotal factors in most types of cancer. Recent cancer research focused on miRNAs has identified and characterized a large cohort of miRNAs commonly dysregulated in cancer or exclusively dysregulated in specific types of cancer. These studies have suggested the potential of miRNAs as biomarkers in the diagnosis and prognostication of cancer. Moreover, many of these miRNAs have oncogenic…

• NN
  National Natural Science Foundation of China

  Award: 82073120
• ST
  Science, Technology and Innovation Commission of Shenzhen Municipality

  Award: 20200812161921001
• NC
  National Cancer Institute

  Award: CA197706