Leveraging artificial intelligence in the fight against infectious diseases

Despite advances in molecular biology, genetics, computation, and medicinal chemistry, infectious disease remains an ominous threat to public health. Addressing the challenges posed by pathogen outbreaks, pandemics, and antimicrobial resistance will require concerted interdisciplinary efforts. In conjunction with systems and synthetic biology, artificial intelligence (AI) is now leading to rapid progress, expanding anti-infective drug discovery, enhancing our understanding of infection biology, and accelerating the development of diagnostics. In this Review, we discuss approaches for detecting, treating, and understanding infectious diseases, underscoring the progress supported by AI in each case. We suggest…

• IA
  International Association for Dental Research
• UO
  University of Pennsylvania
• UT
  United Therapeutics Corporation
• BI
  Broad Institute
• NI
  National Institutes of Health
• DT
  Defense Threat Reduction Agency
• PS
  Perelman School of Medicine, University of Pennsylvania
• NI
  National Institute of General Medical Sciences
• NI
  National Institute of Allergy and Infectious Diseases