reviewBiologyJul 13, 2023GOLD OA

Next-Generation Sequencing Technology: Current Trends and Advancements

University of Massachusetts Chan Medical School

PubMed
Indexed incrossrefdoajpubmed

Abstract

The advent of next-generation sequencing (NGS) has brought about a paradigm shift in genomics research, offering unparalleled capabilities for analyzing DNA and RNA molecules in a high-throughput and cost-effective manner. This transformative technology has swiftly propelled genomics advancements across diverse domains. NGS allows for the rapid sequencing of millions of DNA fragments simultaneously, providing comprehensive insights into genome structure, genetic variations, gene expression profiles, and epigenetic modifications. The versatility of NGS platforms has expanded the scope of genomics research, facilitating studies on rare genetic diseases, cancer genomics, microbiome analysis, infectious diseases,…

Citation impact

1,146
total citations
FWCI
166.31
Percentile
100%
References
207
Citations per year

Authors

11

Topics & keywords

Keywords
  • Biology
  • Genomics
  • DNA sequencing
  • Computational biology
  • Precision medicine
  • Scope (computer science)
  • Data science
  • Genome
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