reviewMedCommJul 14, 2023GOLD OA

Nanoparticles‐induced potential toxicity on human health: Applications, toxicity mechanisms, and evaluation models

Central South University · Zero to Three · +2 more institutions

PubMed
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Abstract

Nanoparticles (NPs) have become one of the most popular objects of scientific study during the past decades. However, despite wealth of study reports, still there is a gap, particularly in health toxicology studies, underlying mechanisms, and related evaluation models to deeply understanding the NPs risk effects. In this review, we first present a comprehensive landscape of the applications of NPs on health, especially addressing the role of NPs in medical diagnosis, therapy. Then, the toxicity of NPs on health systems is introduced. We describe in detail the effects of NPs on various systems, including respiratory, nervous, endocrine, immune, and reproductive systems, and the carcinogenicity of NPs.…

Citation impact

668
total citations
FWCI
60.43
Percentile
100%
References
407
Citations per year

Authors

5

Topics & keywords

Keywords
  • Toxicity
  • Human health
  • Mechanism (biology)
  • Nanotoxicology
  • Nanomedicine
  • Nanotechnology
  • DNA damage
  • Computational biology
UN Sustainable Development Goals
  • Good health and well-being
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Funding