Transformer Architecture and Attention Mechanisms in Genome Data Analysis: A Comprehensive Review

The emergence and rapid development of deep learning, specifically transformer-based architectures and attention mechanisms, have had transformative implications across several domains, including bioinformatics and genome data analysis. The analogous nature of genome sequences to language texts has enabled the application of techniques that have exhibited success in fields ranging from natural language processing to genomic data. This review provides a comprehensive analysis of the most recent advancements in the application of transformer architectures and attention mechanisms to genome and transcriptome data. The focus of this review is on the critical evaluation of these techniques, discussing their…

• NR
  National Research Foundation
• NR
  National Research Foundation of Korea

  Award: RS-2023-00251528
• MO
  Ministry of Science and ICT, South Korea