reviewChemical ReviewsAug 1, 2023Closed access

Rhodium-Catalyzed Asymmetric C–H Functionalization Reactions

Shanghai Institute of Organic Chemistry · University of Chinese Academy of Sciences

PubMed
Indexed incrossrefpubmed

Abstract

This review summarizes the advancements in rhodium-catalyzed asymmetric C-H functionalization reactions during the last two decades. Parallel to the rapidly developed palladium catalysis, rhodium catalysis has attracted extensive attention because of its unique reactivity and selectivity in asymmetric C-H functionalization reactions. In recent years, Rh-catalyzed asymmetric C-H functionalization reactions have been significantly developed in many respects, including catalyst design, reaction development, mechanistic investigation, and application in the synthesis of complex functional molecules. This review presents an explicit outline of catalysts and ligands, mechanism, the scope of coupling reagents, and…

No related works found for this paper.

Funding