The dawn of spatial omics
Cancer Research UK · Cancer Research UK Cambridge Center
Abstract
Spatial omics has been widely heralded as the new frontier in life sciences. This term encompasses a wide range of techniques that promise to transform many areas of biology and eventually revolutionize pathology by measuring physical tissue structure and molecular characteristics at the same time. Although the field came of age in the past 5 years, it still suffers from some growing pains: barriers to entry, robustness, unclear best practices for experimental design and analysis, and lack of standardization. In this Review, we present a systematic catalog of the different families of spatial omics technologies; highlight their principles, power, and limitations; and give some perspective and suggestions on…
Citation impact
- FWCI
- 77.79
- Percentile
- 100%
- References
- 129
Authors
3Topics & keywords
- Data science
- Omics
- Robustness (evolution)
- Standardization
- Frontier
- Computer science
- Computational biology
- Biology
Funding
- WTWellcome TrustAward: BRC-1215-20014
- CRCancer Research UKAwards: BRC-1215-20014, A24042, C9545, A21143, C9545/A29580
- NINational Institute for Health and Care ResearchAward: BRC-1215-20014
- DODepartment of Health and Social Care
- NCNIHR Cambridge Biomedical Research CentreAward: BRC-1215-20014
- CRCancer Research UK Cambridge Institute, University of CambridgeAwards: A29580, C9545/A29580