Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation

Geffen, Yifat; Anand, Shankara; Akiyama, Yo; Yaron, Tomer M.; Song, Yizhe; Johnson, Jared L.; Govindan, Akshay; Babur, Özgün; Li, Yize; Huntsman, Emily M.; Wang, Liang-Bo; Birger, Chet; Heiman, David I.; Zhang, Qing; Miller, Mendy; Maruvka, Yosef E.; Haradhvala, Nicholas J.; Calinawan, Anna; Belkin, Saveliy; Kerelsky, Alexander; Clauser, Karl R.; Krug, Karsten; Satpathy, Shankha; Payne, Samuel; Mani, D.R.; Gillette, Michael A.; Dhanasekaran, Saravana M.; Thiagarajan, Mathangi; Mesri, Mehdi; Rodriguez, Henry; Robles, Ana I.; Carr, Steven A.; Lazar, Alexander J.; Aguet, François; Cantley, Lewis C.; Ding, Li; Getz, Gad; An, Eunkyung; Anurag, Meenakshi; Bavarva, Jasmin; Birrer, Michael J.; Babur, Özgün; Cao, Song; Ceccarelli, Michele; Chan, Daniel W.; Chinnaiyan, Arul M.; Cho, Hanbyul; Chowdhury, Shrabanti; Cieślik, Marcin; Colaprico, Antonio; Carr, Steven A.; Leprevost, Felipe da Veiga; Day, Corbin; Domagalski, Marcin J.; Dou, Yongchao; Druker, Brian; Edwards, Nathan; Ellis, Matthew J.; Fenyö, David; Foltz, Steven M.; Francis, Alicia; González-Robles, Tania J; Gosline, Sara J.C.; Gümüş, Zeynep H.; Hiltke, Tara; Hong, Runyu; Hostetter, Galen; Hu, Yingwei; Huang, Chen; Iavarone, Antonio; Jaehnig, Eric J.; Jewel, Scott; Ji, Jiayi; Jiang, Wen; Katsnelson, Lizabeth; Ketchum, Karen A.; Kołodziejczak, Iga; Kumar‐Sinha, Chandan; Krug, Karsten; Lei, Jonathan T.; Liang, Wen-Wei; Liao, Yuxing; Lindgren, Caleb M.; Liu, Tao; Liu, Wenke; Ma, Weiping; McKerrow, Wilson; Mesri, Mehdi; Mani, D.R.; Nesvizhskii, Alexey I.; Newton, Chelsea J.; Oldroyd, Robert; Omenn, Gilbert S.; Paulovich, Amanda G.; Petralia, Francesca; Pugliese, Pietro; Reva, Boris; Rodland, Karin; Ruggles, Kelly V.; Rykunov, Dmitry; Rodrigues, Fernanda Martins; Savage, Sara R.; Schadt, Eric E.; Schnaubelt, Michael; Schraink, Tobias; Shi, Zhiao; Smith, Richard; Song, Xiaoyu; Stathias, Vasileios; Storrs, Erik; Schürer, Stephan C.; Selvan, Myvizhi Esai; Tan, Jimin; Terekhanova, Nadezhda V.; Thangudu, Ratna R.; Tignor, Nicole; Thiagarajan, Mathangi; Wang, Joshua M.; Wang, Pei; Wang, Ying; Wen, Bo; Wiznerowicz, Maciej; Wu, Yige; Wyczalkowski, Matthew A.; Yao, Lijun; Yi, Xinpei; Yao, Lijun; Zhang, Bing; Zhang, Hui; Zhang, Xu; Zhang, Zhen; Zhou, Daniel Cui

doi:10.1016/j.cell.2023.07.013

articleCellAug 1, 2023BRONZE OA

Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation

YGYifat Geffen SAShankara Anand YAYo Akiyama TMTomer M. Yaron YSYizhe Song

Broad Institute · Massachusetts General Hospital · +14 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

179

total citations

FWCI: 26.01
Percentile: 100%
References: 192

Citations per year

Authors

132

YG
Yifat Geffen
Broad Institute, Massachusetts General Hospital, Massachusetts Institute of Technology
SA
Shankara Anand
Broad Institute, Massachusetts Institute of Technology
YA
Yo Akiyama
Broad Institute, Massachusetts Institute of Technology
TM
Tomer M. Yaron
Cornell University
YS
Yizhe Song
Washington University in St. Louis

Topics & keywords

Topics

Ubiquitin and proteasome pathways100%
RNA modifications and cancer100%
Cancer-related Molecular Pathways100%

Keywords

Biology
Posttranslational modification
Cancer
Computational biology
Genetics
Biochemistry
Enzyme

No related works found for this paper.

Funding

UD
U.S. Department of Health and Human Services
Award: 75N91019D00024
IB
International Business Machines Corporation
BI
Broad Institute
NI
National Institutes of Health
Awards: 75N91019D00024, U24CA210955, 75N91020F00029, U24CA210985, U24CA210954, U24CA210972, U24CA210986, U01CA214114, U24CA210967, U01CA214116, P01CA206978, U01CA214125, U24CA210979, U24CA210993
NC
National Cancer Institute
Awards: U24CA210993, U01CA214116, U24CA210986, U24CA210954, 75N91019D00024, U24CA210972, U24CA210985, U01CA214114, U24CA210979, U01CA214125, U24CA210967, U24CA210955