Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties

The treatment of chronic and non-healing wounds in diabetic patients remains a major medical problem. Recent reports have shown that hydrogel wound dressings might be an effective strategy for treating diabetic wounds due to their excellent hydrophilicity, good drug-loading ability and sustained drug release properties. As a typical example, hyaluronic acid dressing (Healoderm) has been demonstrated in clinical trials to improve wound-healing efficiency and healing rates for diabetic foot ulcers. However, the drug release and degradation behavior of clinically-used hydrogel wound dressings cannot be adjusted according to the wound microenvironment. Due to the intricacy of diabetic wounds, antibiotics and other…

• NN
  National Natural Science Foundation of China

  Awards: 2019031, 82173750, 81971724, 81773661, 81972081, 2020YFA0908100, 51973226
• YI
  Youth Innovation Promotion Association of the Chinese Academy of Sciences

  Award: 2019031
• KT
  Key Technologies Research and Development Program

  Award: 2020YFA0908100
• NK
  National Key Research and Development Program of China

  Award: 2020YFA0908100
• YI
  Youth Innovation Promotion Association

  Award: 2019031