Nitric Oxide: Physiological Functions, Delivery, and Biomedical Applications

Nitric oxide (NO) is a gaseous molecule that has a central role in signaling pathways involved in numerous physiological processes (e.g., vasodilation, neurotransmission, inflammation, apoptosis, and tumor growth). Due to its gaseous form, NO has a short half-life, and its physiology role is concentration dependent, often restricting its function to a target site. Providing NO from an external source is beneficial in promoting cellular functions and treatment of different pathological conditions. Hence, the multifaceted role of NO in physiology and pathology has garnered massive interest in developing strategies to deliver exogenous NO for the treatment of various regenerative and biomedical complexities.…

• UO
  University of Nebraska Medical Center

  Award: NE LB606
• NI
  National Institutes of Health

  Awards: R01DE031272, R01GM138552, NE LB606, LB606, P30GM127200
• NI
  National Institute of General Medical Sciences

  Awards: R01GM138552, P30GM127200, NE LB606
• NI
  National Institute of Dental and Craniofacial Research

  Award: R01DE031272
• CD
  Congressionally Directed Medical Research Programs

  Awards: FY19 W81XWH2010207, W81XWH2010207