articleNew England Journal of MedicineAug 26, 2023GREEN OA

Extracorporeal Life Support in Infarct-Related Cardiogenic Shock

Universität Hamburg · Heidelberg University · +28 more institutions

PubMed
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Abstract

Background

Extracorporeal life support (ECLS) is increasingly used in the treatment of infarct-related cardiogenic shock despite a lack of evidence regarding its effect on mortality.

Methods

In this multicenter trial, patients with acute myocardial infarction complicated by cardiogenic shock for whom early revascularization was planned were randomly assigned to receive early ECLS plus usual medical treatment (ECLS group) or usual medical treatment alone (control group). The primary outcome was death from any cause at 30 days. Safety outcomes included bleeding, stroke, and peripheral vascular complications warranting interventional or surgical therapy.

Citation impact

729
total citations
FWCI
75.50
Percentile
100%
References
25
Citations per year

Authors

35

Topics & keywords

Keywords
  • Cardiogenic shock
  • Extracorporeal
  • Cardiology
  • Myocardial infarction
  • Life support
  • Internal medicine
  • Medicine
  • Shock (circulatory)
UN Sustainable Development Goals
  • Good health and well-being
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Funding