Multifunctional Hydrogels for the Healing of Diabetic Wounds
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Abstract
Abstract The healing of diabetic wounds is hindered by various factors, including bacterial infection, macrophage dysfunction, excess proinflammatory cytokines, high levels of reactive oxygen species, and sustained hypoxia. These factors collectively impede cellular behaviors and the healing process. Consequently, this review presents intelligent hydrogels equipped with multifunctional capacities, which enable them to dynamically respond to the microenvironment and accelerate wound healing in various ways, including stimuli ‐responsiveness, injectable self‐healing, shape ‐memory, and conductive and real‐time monitoring properties. The relationship between the multiple functions and wound healing is also…
Citation impact
234
total citations
- FWCI
- 30.59
- Percentile
- 100%
- References
- 425
Citations per year
Authors
7Topics & keywords
Topics
Keywords
- Self-healing hydrogels
- Proinflammatory cytokine
- Wound healing
- Hypoxia (environmental)
- Reactive oxygen species
- Inflammation
- Medicine
- Materials science
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