Amino acid metabolism in health and disease
Chinese Academy of Medical Sciences & Peking Union Medical College · Blood Center of Zhejiang Province · +3 more institutions
Abstract
Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth, differentiation and function. Amino acid metabolism disorders have been linked with a number of pathological conditions, including metabolic diseases, cardiovascular diseases, immune diseases, and cancer. In the case of tumors, alterations in amino acid metabolism can be used not only as clinical indicators of cancer progression but also as therapeutic strategies. Since the growth and development of tumors depend on the intake of foreign amino acids, more and more studies have targeted the metabolism of tumor-related amino acids to selectively kill tumor cells.…
Citation impact
- FWCI
- 68.18
- Percentile
- 100%
- References
- 356
Authors
6- ZLZhenan LingCorresponding
Chinese Academy of Medical Sciences & Peking Union Medical College, Blood Center of Zhejiang Province, First Affiliated Hospital Zhejiang University, Zhejiang University
- YJYifan Jiang
Chinese Academy of Medical Sciences & Peking Union Medical College, Blood Center of Zhejiang Province, First Affiliated Hospital Zhejiang University, Zhejiang University
- JRJun-Nan Ru
Chinese Academy of Medical Sciences & Peking Union Medical College, Blood Center of Zhejiang Province, First Affiliated Hospital Zhejiang University, Zhejiang University
- JLJia-Hua Lu
Chinese Academy of Medical Sciences & Peking Union Medical College, Blood Center of Zhejiang Province, First Affiliated Hospital Zhejiang University, Zhejiang University
- BDBo Ding
Chinese Academy of Medical Sciences & Peking Union Medical College, Blood Center of Zhejiang Province, First Affiliated Hospital Zhejiang University, Zhejiang University
Topics & keywords
- Amino acid metabolism
- Amino acid
- Metabolism
- Disease
- Biochemistry
- Computational biology
- Biology
- Bioinformatics