Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Chen, Yanhua; Du, Xiaomeng; Kuppa, Annapurna; Feitosa, Mary F.; Bielak, Lawrence F.; O’Connell, Jeffrey R.; Musani, Solomon K.; Guo, Xiuqing; Kahali, Bratati; Chen, Vincent; Smith, Albert V.; Ryan, Kathleen A.; Eirksdottir, Gudny; Allison, Matthew; Bowden, Donald W.; Budoff, Matthew J.; Carr, J. Jeffrey; Chen, Yii‐Der Ida; Taylor, Kent D.; Oliveri, Antonino; Correa, Adolfo; Crudup, Breland; Kardia, Sharon L. R.; Mosley, Thomas H.; Norris, Jill M.; Terry, James G.; Rotter, Jerome I.; Wagenknecht, Lynne E.; Halligan, Brian; Young, Kendra A.; Hokanson, John E.; Washko, George R.; Guðnason, Vilmundur; Province, Michael A.; Peyser, Patricia A.; Palmer, Nicholette D.; Speliotes, Elizabeth K.

doi:10.1038/s41588-023-01497-6

reviewNature GeneticsSep 14, 2023GREEN OA

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

YCYanhua Chen XDXiaomeng Du AKAnnapurna Kuppa MFMary F. Feitosa LFLawrence F. Bielak

University of Michigan · UCLA Medical Center · +13 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

197

total citations

FWCI: 41.55
Percentile: 100%
References: 114

Citations per year

Authors

YC
Yanhua ChenCorresponding
University of Michigan, UCLA Medical Center, Harbor–UCLA Medical Center
XD
Xiaomeng Du
University of Michigan
AK
Annapurna Kuppa
University of Michigan
MF
Mary F. Feitosa
LF
Lawrence F. Bielak
University of Michigan

Topics & keywords

Topics

Liver Disease Diagnosis and Treatment100%
Genetic Associations and Epidemiology100%
Endoplasmic Reticulum Stress and Disease100%

Keywords

Biology
Nonalcoholic fatty liver disease
Genome-wide association study
Genetics
Meta-analysis
Genetic association
Nonalcoholic steatohepatitis
Disease

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.

Funding

UD
U.S. Department of Defense
Award: UL1TR001881
A
AstraZeneca
B
Biogen
VU
Vanderbilt University
JS
Jackson State University
Awards: HHSN268201800013I, HHSN268201800014I
UO
University of Michigan
VU
Vanderbilt University Medical Center
BI
Broad Institute
KC
Kowa Company
MS
Mississippi State Department of Health
Award: HHSN268201800015I
H
Hjartavernd
Awards: HHSN271201200022C, N01-AG-1-2100
NI
National Institutes of Health
Awards: R01 DK106621, RO1 DK107904, 75N92020D00005, 75N92020D00003, HHSN268201800010I, HHSN268201800011I, 75N92019D00031, U01 HL072515, HL060894, N01-HC-95161, U01 HL84756, N01-HC-95169, HHSN271201200022C, HHSN268201800012I, N01-HC-95166, N01-HC-95164, HHSN268201800014I, R01 DK089256, N02-HL64278, UL1-TR-001420, N01-AG-1-2100, UL1-TR-001079, 75N92020D00006, UL1TR001881, R01HL105756, N01-HC-95165, HL061019, N02-HL-64278, N01-HC-95163, UL1-TR-000040, P30 DK72488, N01-HC-95168, U01 HL137181, DK063491, HHSN268201800013I, HL060944, HL085571, HHSN268201500003I, 75N92020D00004, N01-HC-25195, N01-HC-95160, N01-HC-95159, HL060919, 75N92020D00007, HHSN268201800015I, N01-HC-95167, 75N92020D00001, N01-HC-95162, 75N92020D00002, HHSN268201500001I, UL1-TR-, R01 HL071739, HL087660
MS
Medical School, University of Michigan
NI
National Institute on Aging
Awards: N01-HC-95166, N01-HC-95161, 75N92020D00007, N01-HC-95169, UL1TR001881, N01-HC-95167, N01-HC-25195, N01-HC-95168, 75N92020D00005, 75N92020D00001, N01-HC-95162, 75N92020D00006, N01-HC-95165, 75N92020D00003, N01-HC-95163, N01-HC-95164, 75N92020D00004, 75N92020D00002, HHSN268201500003I, N01-HC-95160, N01-HC-95159, HHSN271201200022C, N01-AG-1-2100
NH
National Heart, Lung, and Blood Institute
Awards: N01-HC-95160, HHSN268201800013I, 75N92020D00001, UL1-TR-001420, 75N92020D00006, N01-HC-95166, HL085571, HL060944, N01-HC-95169, UL1TR001881, N02-HL-64278, 75N92020D00007, N01-HC-95165, HHSN268201500001I, 75N92020D00002, N01-HC-95167, N01-HC-95159, UL1-TR-000040, 75N92020D00005, HHSN268201800010I, 75N92019D00031, HHSN268201800014I, 75N92020D00003, N01-HC-95164, UL1-TR-001079, N01-HC-25195, R01HL105756, HHSN268201800012I, N01-HC-95163, HHSN268201800015I, HL061019, R01 HL071739, U01 HL072515, R01 HL117078, HL087660, N01-HC-95168, N01-HC-95162, N02-HL64278, HHSN268201800011I, DK063491, N01-HC-95161, HL060919, HL071739, HHSN268201500003I, 75N92020D00004
NI
National Institute of Diabetes and Digestive and Kidney Diseases
Awards: 75N92020D00005, DK063491, N01-HC-25195, DK085175, R01 DK089256, UL1-TR-001079, HHSN268201500001I, DK118062, DK089256, P30 DK72488, 75N92019D00031, UL1-TR-000040
NI
National Institute on Minority Health and Health Disparities
Awards: HHSN268201800012I, HHSN268201800010I, HHSN268201800014I, HHSN268201800015I, HHSN268201800011I, HHSN268201800013I
JP
Janssen Pharmaceuticals