The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring
Harvard University · Massachusetts General Hospital · +13 more institutions
Abstract
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for cancer and other diseases. Liquid biopsy allows minimally invasive molecular characterization of cancers for diagnosis, patient stratification to therapy, and longitudinal monitoring. Liquid biopsy strategies include detection and monitoring of circulating tumor cells, cell-free DNA, and extracellular vesicles. In this review, we address the current understanding and the role of existing liquid-biopsy-based modalities in cancer diagnostics and monitoring. We specifically focus on the technical and clinical challenges associated with liquid biopsy and biomarker development being addressed by the Liquid Biopsy…
Citation impact
- FWCI
- 44.96
- Percentile
- 100%
- References
- 122
Authors
48- SMSyeda Maheen Batool
Harvard University, Massachusetts General Hospital
- AYAnudeep Yekula
Harvard University, Massachusetts General Hospital
- PKPrerna Khanna
Harvard University, Massachusetts General Hospital
- THTiffaney Hsia
Harvard University, Massachusetts General Hospital
- ASAustin S. Gamblin
Harvard University, Massachusetts General Hospital
Topics & keywords
- Liquid biopsy
- Cancer detection
- Medicine
- Cancer
- Medical physics
- Business
- Internal medicine