Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics
Bharati Vidyapeeth Deemed University · Agharkar Research Institute · +3 more institutions
Abstract
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug therapy. But presently, detailed investigations have revealed their flaws as drug delivery carriers. Lipid polymer hybrid nanoparticles (LPHNPs) are advanced core-shell nanoconstructs with a polymeric core region enclosed by a lipidic layer, presumed to be derived from both liposomes and polymeric nanounits. This unique concept is of utmost importance as a combinable drug delivery platform in oncology due to its dual structured character. To add advantage and restrict one's limitation by other, LPHNPs have been designed so to gain number of advantages such as stability, high loading of cargo, increased biocompatibility,…
Citation impact
- FWCI
- 20.75
- Percentile
- 100%
- References
- 307
Authors
6Topics & keywords
- Biology
- Nanoparticle
- Cancer
- Computational biology
- Nanotechnology
- Materials science
- Polymer
- Cancer research