Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Brigham and Women's Hospital · Harvard University · +161 more institutions
Abstract
Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous problem by accounting for heterogeneity in the etiology, clinical presentation and pathogenesis of common forms of diabetes and risks of complications. This second international consensus report on precision diabetes medicine summarizes the findings from a systematic evidence review across the key pillars of precision…
Citation impact
- FWCI
- 34.93
- Percentile
- 100%
- References
- 62
Authors
200Topics & keywords
- Precision medicine
- Medicine
- MEDLINE
- Evidence-based medicine
- Intensive care medicine
- Common cause and special cause
- Alternative medicine
- Pathology
Funding
- ADAmerican Diabetes AssociationAwards: DK078616, 7-21-JDFM-005, 9-22-PDFPM-04, 1-15-ACE-26, Pathways Award #1-15-ACE-26, 7-22-ICTSPM-23
- UDU.S. Department of Veterans AffairsAward: IK2-CX001907
- DDDoris Duke Charitable FoundationAwards: 2020096, U54DK118612, 62288, 2021258
- JTJohn Templeton FoundationAward: 62288
- AHAmerican Heart AssociationAwards: H2020, 20SFRN35120152, P30 DK097512, K24 HL152440, COVID-19, P30DK036836
- ELEli Lilly and Company
- PPfizer
- AAstraZeneca
- SSanofi
- YUYale University
- BFBoettcher Foundation
- LMLeona M. and Harry B. Helmsley Charitable TrustAwards: P30 DK097512, 2103-05094
- HYHelsingin Yliopisto
- HHHamilton Health Sciences
- WTWellcome TrustAwards: RE/18/5/34216, 214205, 223024/Z/21/Z, 223187/Z/21/Z, 219606/Z/19/Z, 223187, 214205/Z/18/Z, 200837/Z/16/Z, 200837, 219606, 223024
- PEPediatric Endocrine SocietyAward: KL2TR002490
- ITImmune Tolerance Network
- BBBigfoot Biomedical
- ICInsulet Corporation
- MCMannKind Corporation
- AGAustralian Government
- DDexcom
- TMTrond Mohn stiftelseAward: TMS2022TMT01
- DRDiabetes Research ConnectionAward: DK063491
- NINational Institute for Health and Care ResearchAward: 19/005971
- BHBritish Heart FoundationAwards: RG/17/12/33167, RE/18/5/34216, 2009-1039
- DUDiabetes UKAwards: 19/005971, 21/0006277
- ECEuropean CommissionAwards: 219606, H2020, 681742, 115974, 293574, COVID-19, 223024, EU H2020, ERC-CoG_NASCENT-681742, 200837
- CFCroucher Foundation
- SFStiftelsen för Strategisk ForskningAwards: 2009-1039, LUDC-IRC, 15-0067
- AOAcademy of FinlandAwards: 336826, 312072, EU H2020, 336826
- AFAlbert-Ludwigs-Universität Freiburg
- MDMinistero della SaluteAwards: 2018-, GR-2019-12369702
- LULunds UniversitetAward: 2009-1039
- IAInnovation and Technology Commission
- HHjärt-LungfondenAward: 20190470
- KLKU Leuven
- NNNovo NordiskAwards: 54741, NNF18CC0034900
- VVetenskapsrådetAwards: 2009-1039, 2019-01348, 2014-03529, 2018-, 2018-02837
- NHNational Health Research Institutes
- CUChinese University of Hong Kong
- NFNorges ForskningsrådAwards: 293574, 240413
- EAEuropean Association for the Study of Diabetes
- DDiabetesforbundet
- NNNovo Nordisk FondenAwards: 293574, NNF18CC0034900, 54741
- NNNovo Nordisk Foundation Center for Basic Metabolic ResearchAward: NNF18CC0034900
- SPSun Pharma
- HKHong Kong Government
- NINational Institutes of HealthAwards: P30 DK40561, R25HL146166, K24 HL152440, 5R01DK124806, 2103-05094, NIH K01, T32HL007024, UG1 HD107691, R01DK122586, UM-1DK126185, RE/18/5/34216, U01 DK078616, NIH K24, KL2TR002490, DK097512, COVID-19, DK063491, R01 DK124395, P30DK036836, DK078616, DK40561, R01 DK121843-01, U54DK118612, K23-DK129821, R01DK034818, P30-DK063491, P30 DK097512, K23DK114551, NIH R03, 20SFRN35120152, K23DK133690, R01 DK121843, K24 HL157960, T32DK007028, R01DK104942, 2021258, H2020
- MSMerck Sharp and Dohme
- H2Horizon 2020 Framework ProgrammeAwards: NNF18CC0034900, 115974, P30-DK063491, EU H2020
- CICanadian Institutes of Health ResearchAwards: RE/18/5/34216, P30-DK063491, COVID-19, U01 DK078616
- MRMedical Research CouncilAwards: MR/W003740/1, MC_UU_00014/4, EU H2020, MC_UU_00014/4, MR/T016701/1, MR/V034294/1, COVID-19, MR/W003740/1
- NHNational Health and Medical Research CouncilAward: 2000905
- NINIHR Imperial Biomedical Research Centre
- REResearch England
- NHNational Heart, Lung, and Blood InstituteAwards: HL152440, K24 HL152440, R25HL146166, K24 HL157960, DK078616, 20SFRN35120152, HL151855, DK063491, T32HL007024, R01 HL151855
- NHNational Human Genome Research InstituteAwards: U24HD093486, 2020096, U01HG007775
- NINational Institute of General Medical SciencesAwards: P30DK036836, 1-15-ACE-26, RE/18/5/34216
- NINational Institute of Allergy and Infectious DiseasesAwards: COVID-19, P30 DK40561, KL2TR002490
- NINational Institute of Diabetes and Digestive and Kidney DiseasesAwards: 20SFRN35120152, P30DK036836, DK063491, R01 DK121843, R01DK125780, DK078616, T32DK007028, P30 DK40561, R01DK134955, U54DK118612, P30-DK063491, R21DK125888, U01 DK078616, K23-DK129821, K23DK128572, DK124395, UG1 HD107691, DK40561, DK121843, K23DK114551, R01DK122586, P30 DK097512, K23DK133690, R01 HL151855, R01 DK121843-01, K23DK129799, 115974, K24 HL152440, DK097512, UM-1DK126185, R01 DK124395, R01DK104942
- NCNational Center for Advancing Translational SciencesAwards: DK063491, KL2TR002490
- CFCenter for Duchenne Muscular Dystrophy, University of California, Los Angeles
- EKEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentAwards: R01 DK121843, DK063491, 1 R01, KL2TR002490, R01 DK124395, U24HD093486
- MRMoonshot Research and Development Program
- DSDaiichi Sankyo Europe