Gut microbiota in the pathogenesis and therapeutic approaches of diabetes
University of Bari Aldo Moro · Istituto Nazionale Biostrutture e Biosistemi
Abstract
The gut-liver axis plays a prominent role in the pathogenesis and therapy of metabolic diseases such as diabetes. The intestinal specific origin of several hormones that guide both inter- and post-prandial metabolism of carbohydrates and lipids, drives the attention of scientists and clinicians on the gut as a major site to intervene with novel diagnostic or prognostic markers. The role of intestinal ecology in the metabolic syndrome was postulated when gut microbiota was directly connected with inflammation, hyperinsulinemia, and diabetes. There have been several discoveries with the role of gut microbiota and gut-liver axis in diabetes. Also, there are several trials ongoing on the therapeutic efficacy of…
Citation impact
- FWCI
- 33.03
- Percentile
- 100%
- References
- 78
Authors
4Topics & keywords
- Gut flora
- Diabetes mellitus
- Pathogenesis
- Probiotic
- Hyperinsulinemia
- Bioinformatics
- Metabolic syndrome
- Fatty liver
- Good health and well-being