Stimuli-activatable nanomedicine meets cancer theranostics

Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics. Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine could be self-assembled, disassembled, or functionally activated to improve its biosafety and diagnostic/therapeutic potency. A myriad of tumor-specific features, including a low pH, a high redox level, and overexpressed enzymes, along with exogenous physical stimulation sources (light, ultrasound, magnet, and radiation) have been considered for the design of stimuli-activatable nano-medicinal products. Recently, novel stimuli sources have been explored and elegant designs emerged for stimuli-activatable nanomedicine. In addition,…

• NN
  National Natural Science Foundation of China

  Awards: 52073193, 81621003, 82202310, 51873120, ZYJC21013
• SU
  Sichuan University

  Awards: ZYJC21013, 51873120, 52073193, 81621003
• WC
  West China Hospital, Sichuan University

  Awards: 81621003, 52073193, ZYJC21013, 51873120