Macrophage polarization and metabolism in atherosclerosis
University of Rome Tor Vergata · Soochow University · +1 more institution
Abstract
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty deposits in the inner walls of vessels. These plaques restrict blood flow and lead to complications such as heart attack or stroke. The development of atherosclerosis is influenced by a variety of factors, including age, genetics, lifestyle, and underlying health conditions such as high blood pressure or diabetes. Atherosclerotic plaques in stable form are characterized by slow growth, which leads to luminal stenosis, with low embolic potential or in unstable form, which contributes to high risk for thrombotic and embolic complications with rapid clinical onset. In this complex scenario of atherosclerosis, macrophages…
Citation impact
- FWCI
- 44.56
- Percentile
- 100%
- References
- 193
Authors
16- PHPengbo HouCorresponding
University of Rome Tor Vergata, Soochow University, First Affiliated Hospital of Soochow University
- JFJiankai Fang
Soochow University, First Affiliated Hospital of Soochow University
- ZLZhanhong Liu
University of Rome Tor Vergata, Soochow University, First Affiliated Hospital of Soochow University
- YSYufang Shi
Soochow University, First Affiliated Hospital of Soochow University
- MAMassimiliano Agostini
University of Rome Tor Vergata
Topics & keywords
- Macrophage polarization
- Macrophage
- Inflammation
- Biology
- Cancer research
- Cell biology
- Medicine
- Pathology
- Good health and well-being