articleNucleic Acids ResearchNov 11, 2023GOLD OA

DGIdb 5.0: rebuilding the drug–gene interaction database for precision medicine and drug discovery platforms

MCMatthew CannonJSJames StevensonKSKathryn StahlRBRohit BasuACAdam Coffman

Nationwide Children's Hospital · Washington University in St. Louis · +1 more institution

PubMed
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Abstract

The Drug-Gene Interaction Database (DGIdb, https://dgidb.org) is a publicly accessible resource that aggregates genes or gene products, drugs and drug-gene interaction records to drive hypothesis generation and discovery for clinicians and researchers. DGIdb 5.0 is the latest release and includes substantial architectural and functional updates to support integration into clinical and drug discovery pipelines. The DGIdb service architecture has been split into separate client and server applications, enabling consistent data access for users of both the application programming interface (API) and web interface. The new interface was developed in ReactJS, and includes dynamic visualizations and consistency in…

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Topics & keywords

Topics
Keywords
  • Documentation
  • Interface (matter)
  • Interoperability
  • Application programming interface
  • Computer science
  • Database
  • Consistency (knowledge bases)
  • World Wide Web
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