The Human Phenotype Ontology in 2024: phenotypes around the world

The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. The HPO has widespread applications in clinical diagnostics and translational research, including genomic diagnostics, gene-disease discovery, and cohort analytics. In recent years, groups around the world have developed translations of the HPO from English to other languages, and the HPO browser has been internationalized, allowing users to view HPO term labels and in many cases synonyms and definitions in ten languages in…

• UD
  U.S. Department of Energy

  Award: DE-AC02-05CH11231
• WT
  Wellcome Trust

  Award: 203914/Z/16/Z
• MC
  McCusker Charitable Foundation
• DF
  Deutsche Forschungsgemeinschaft

  Award: WY 215/1-1
• BI
  Berlin Institute of Health
• AW
  Angela Wright Bennett Foundation
• NI
  National Institutes of Health

  Awards: K08AG054727, 5R24OD011883-11, 5U24HG011449-03
• DA
  Defense Advanced Research Projects Agency

  Award: W911NF-20-1-0255
• H2
  Horizon 2020 Framework Programme

  Award: 779257
• NI
  National Institute of Mental Health

  Award: U24 MH068457
• NH
  National Human Genome Research Institute

  Award: 7RM1HG010860-02
• NI
  National Institute of Child Health and Human Development

  Award: R01HD105266
• NI
  National Institute of Dental and Craniofacial Research

  Award: R03-DE032062
• UN
  U.S. National Library of Medicine

  Awards: T15LM009451, NLM T15LM007079
• NC
  National Center for Advancing Translational Sciences

  Award: NCATS U24 TR002306