Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy
Sichuan University · State Key Laboratory of Oral Diseases
Abstract
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation of inflammatory responses is associated with most human diseases. Reactive oxygen species (ROS) are a class of chemicals that are generated after the incomplete reduction of molecular oxygen. At moderate levels, ROS function as critical signaling molecules in the modulation of various physiological functions, including inflammatory responses. However, at excessive levels, ROS exert toxic effects and directly oxidize biological macromolecules, such as proteins, nucleic acids and lipids, further exacerbating the development of inflammatory responses and causing various inflammatory diseases. Therefore, designing and…
Citation impact
- FWCI
- 57.47
- Percentile
- 100%
- References
- 252
Authors
6- JLJiatong Liu
Sichuan University, State Key Laboratory of Oral Diseases
- XHXiaoyue Han
Sichuan University, State Key Laboratory of Oral Diseases
- TZTingyue Zhang
Sichuan University, State Key Laboratory of Oral Diseases
- KTKeyue Tian
Sichuan University, State Key Laboratory of Oral Diseases
- ZLZhaoping Li
Sichuan University, State Key Laboratory of Oral Diseases
Topics & keywords
- Reactive oxygen species
- Inflammation
- Cell biology
- Chemistry
- Oxidative stress
- Signal transduction
- Biochemistry
- Immunology