The potential impacts of micro-and-nano plastics on various organ systems in humans
Shahjalal University of Science and Technology · Imperial College London · +4 more institutions
Abstract
Humans are exposed to micro-and-nano plastics (MNPs) through various routes, but the adverse health effects of MNPs on different organ systems are not yet fully understood. This review aims to provide an overview of the potential impacts of MNPs on various organ systems and identify knowledge gaps in current research. The summarized results suggest that exposure to MNPs can lead to health effects through oxidative stress, inflammation, immune dysfunction, altered biochemical and energy metabolism, impaired cell proliferation, disrupted microbial metabolic pathways, abnormal organ development, and carcinogenicity. There is limited human data on the health effects of MNPs, despite evidence from animal and…
Citation impact
- FWCI
- 22.76
- Percentile
- 100%
- References
- 189
Authors
6- NANurshad AliCorresponding
Shahjalal University of Science and Technology, Imperial College London
- JKJenny Katsouli
Imperial College London
- ELEmma L. Marczylo
Public Health England, UK Health Security Agency, MRC Centre for Environment and Health, Imperial College London
- TWTimothy W. Gant
Public Health England, UK Health Security Agency, MRC Centre for Environment and Health, Imperial College London
- SWStephanie Wright
MRC Centre for Environment and Health, Imperial College London
Topics & keywords
- Organ system
- Human health
- Cellular metabolism
- Confounding
- Organ dysfunction
- Immune system
- Inflammation
- Toxicity
Funding
- NINational Institute for Health and Care Research
- DODepartment of Health and Social Care
- ICImperial College London
- MRMedical Research CouncilAwards: MR/X013855/1, MR/R026521/2, MR/X013855/1, MR/W024985/1, MR/W024985/1, MR/R026521/1
- BABiotechnology and Biological Sciences Research CouncilAwards: BB/V019791/1, BB/V019791/1