An NIR‐II Excitable AIE Small Molecule with Multimodal Phototheranostic Features for Orthotopic Breast Cancer Treatment
National University of Singapore · Shenzhen University · +1 more institution
Abstract
One-for-all phototheranostics, referring to a single component simultaneously exhibiting multiple optical imaging and therapeutic modalities, has attracted significant attention due to its excellent performance in cancer treatment. Benefitting from the superiority in balancing the diverse competing energy dissipation pathways, aggregation-induced emission luminogens (AIEgens) are proven to be ideal templates for constructing one-for-all multimodal phototheranostic agents. However, to this knowledge, the all-round AIEgens that can be triggered by a second near-infrared (NIR-II, 1000-1700 nm) light have not been reported. Given the deep tissue penetration and high maximum permissible exposure of the NIR-II…
Citation impact
- FWCI
- 21.00
- Percentile
- 100%
- References
- 32
Authors
13Topics & keywords
- Photothermal therapy
- Materials science
- Near-infrared spectroscopy
- Aggregation-induced emission
- Nanotechnology
- Nanoparticle
- In vivo
- Fluorescence
- Good health and well-being