A tough, antibacterial and antioxidant hydrogel dressing accelerates wound healing and suppresses hypertrophic scar formation in infected wounds

Wound management is an important issue that places enormous pressure on the physical and mental health of patients, especially in cases of infection, where the increased inflammatory response could lead to severe hypertrophic scars (HSs). In this study, a hydrogel dressing was developed by combining the high strength and toughness, swelling resistance, antibacterial and antioxidant capabilities. The hydrogel matrix was composed of a double network of polyvinyl alcohol (PVA) and agarose with excellent mechanical properties. Hyperbranched polylysine (HBPL), a highly effective antibacterial cationic polymer, and tannic acid (TA), a strong antioxidant molecule, were added to the hydrogel as functional components.…

• SI
  Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering

  Award: 2021SZ-TD004
• NN
  National Natural Science Foundation of China
• JF
  Joint Fund of the National Natural Science Foundation of China and the Karst Science Research Center of Guizhou Province

  Award: U22A20155
• NS
  Natural Science Foundation of Zhejiang Province

  Award: LD21E030001