reviewTropical Medicine and Infectious DiseaseJan 4, 2024GOLD OA

Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review

AAArwa A. Al-QahtaniAAArwa A. Al-QahtaniFSFatimah S. AlhamlanAAAhmed Ali Al-QahtaniAAAhmed Ali Al-Qahtani

Alfaisal University · Imam Mohammad ibn Saud Islamic University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress excessive inflammation and promote tissue repair. Here, we provide a comprehensive overview of the role of pro-inflammatory and anti-inflammatory ILs in infectious diseases, with a focus on the mechanisms underlying their effects, their diagnostic and therapeutic potential, and emerging trends in IL-based therapies.

Citation impact

240
total citations
FWCI
50.35
Percentile
100%
References
160
Citations per year

Authors

5

Topics & keywords

Keywords
  • Inflammation
  • Immune system
  • Immunology
  • Medicine
  • Inflammatory response
  • Interleukin
  • Anti-inflammatory
  • Cytokine
UN Sustainable Development Goals
  • Good health and well-being
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