articleNucleic Acids ResearchNov 1, 2023GOLD OA

COSMIC: a curated database of somatic variants and clinical data for cancer

ZSZbysław SońdkaNBNidhi Bindal DhirDCDenise Carvalho‐SilvaSJS JupeMMMadhumita Madhumita

Wellcome Sanger Institute

PubMed
Indexed incrossrefdoajpubmed

Abstract

The Catalogue Of Somatic Mutations In Cancer (COSMIC), https://cancer.sanger.ac.uk/cosmic, is an expert-curated knowledgebase providing data on somatic variants in cancer, supported by a comprehensive suite of tools for interpreting genomic data, discerning the impact of somatic alterations on disease, and facilitating translational research. The catalogue is accessed and used by thousands of cancer researchers and clinicians daily, allowing them to quickly access information from an immense pool of data curated from over 29 thousand scientific publications and large studies. Within the last 4 years, COSMIC has substantially expanded its utility by adding new resources: the Mutational Signatures catalogue, the…

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Topics & keywords

Topics
Keywords
  • Biology
  • Somatic cell
  • Genetics
  • Cancer
  • Database
  • Computational biology
  • Gene
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