Pillararene‐Based Stimuli‐Responsive Supramolecular Delivery Systems for Cancer Therapy

Cancer poses a significant challenge to global public health, seriously threatening human health and life. Although various therapeutic strategies, such as chemotherapy (CT), radiotherapy, phototherapy, and starvation therapy, are applied to cancer treatment, their limited therapeutic effect, severe side effects, and unsatisfactory drug release behavior need to be carefully considered. Thus, there is an urgent need to develop efficient drug delivery strategies for improving cancer treatment efficacy and realizing on-demand drug delivery. Notably, pillararenes, as an emerging class of supramolecular macrocycles, possess unique properties of highly tunable structures, superior host-guest chemistry, facile…

• NS
  Natural Science Foundation of Jilin Province

  Award: 20230101052JC
• NN
  National Natural Science Foundation of China

  Awards: 52203138, 52173200