articleNature NanotechnologyJan 11, 2024HYBRID OA

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

DVDamià VianaSTSteven T. WalstonEMEduard Masvidal‐CodinaXIXavi IllaBRBruno Rodríguez‐Meana

Institut Català de Nanociència i Nanotecnologia · Instituto de Salud Carlos III · +13 more institutions

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Abstract

Abstract One of the critical factors determining the performance of neural interfaces is the electrode material used to establish electrical communication with the neural tissue, which needs to meet strict electrical, electrochemical, mechanical, biological and microfabrication compatibility requirements. This work presents a nanoporous graphene-based thin-film technology and its engineering to form flexible neural interfaces. The developed technology allows the fabrication of small microelectrodes (25 µm diameter) while achieving low impedance (∼25 kΩ) and high charge injection (3–5 mC cm − 2 ). In vivo brain recording performance assessed in rodents reveals high-fidelity recordings (signal-to-noise ratio…

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119
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100%
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32

Topics & keywords

Topics
Keywords
  • Microelectrode
  • Materials science
  • Microfabrication
  • Multielectrode array
  • Nanoporous
  • Graphene
  • Biomedical engineering
  • Nanotechnology
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