articleNature CommunicationsJan 13, 2024GOLD OA

A self-powered intracardiac pacemaker in swine model

ZLZhuo LiuYHYiran HuXQXuecheng QuYLYing LiuSCSijing Cheng

Chinese Academy of Sciences · Beijing Institute of Nanoenergy and Nanosystems · +9 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Harvesting biomechanical energy from cardiac motion is an attractive power source for implantable bioelectronic devices. Here, we report a battery-free, transcatheter, self-powered intracardiac pacemaker based on the coupled effect of triboelectrification and electrostatic induction for the treatment of arrhythmia in large animal models. We show that the capsule-shaped device (1.75 g, 1.52 cc) can be integrated with a delivery catheter for implanting in the right ventricle of a swine through the intravenous route, which effectively converts cardiac motion energy to electricity and maintains endocardial pacing function during the three-week follow-up period. We measure in vivo open circuit voltage and short…

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113
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Authors

18

Topics & keywords

Topics
Keywords
  • Intracardiac injection
  • Triboelectric effect
  • Ventricle
  • Defibrillation
  • Medicine
  • Biomedical engineering
  • Cardiology
  • Materials science
UN Sustainable Development Goals
  • Affordable and clean energy
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