Scaffold-based 3D cell culture models in cancer research
American University of Sharjah · Brigham Young University
Abstract
Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. In 3D cell cultures, cancer cells are grown in an environment that more closely mimics the 3D architecture and complexity of in vivo tumors. This approach has revolutionized cancer research by providing a more accurate representation of the tumor microenvironment (TME) and enabling the study of tumor behavior and response to therapies in a more physiologically relevant context. One of the key benefits of 3D cell culture in cancer research is the ability to recapitulate the complex interactions between cancer cells and their…
Citation impact
- FWCI
- 44.09
- Percentile
- 100%
- References
- 191
Authors
3Topics & keywords
- Stromal cell
- 3D cell culture
- Cancer cell
- Tumor microenvironment
- Context (archaeology)
- Cancer
- Scaffold
- Biology