Interindividual- and blood-correlated sweat phenylalanine multimodal analytical biochips for tracking exercise metabolism
Chinese Academy of Sciences · Institute of Semiconductors · +4 more institutions
Abstract
In situ monitoring of endogenous amino acid loss through sweat can provide physiological insights into health and metabolism. However, existing amino acid biosensors are unable to quantitatively assess metabolic status during exercise and are rarely used to establish blood-sweat correlations because they only detect a single concentration indicator and disregard sweat rate. Here, we present a wearable multimodal biochip integrated with advanced electrochemical electrodes and multipurpose microfluidic channels that enables simultaneous quantification of multiple sweat indicators, including phenylalanine and chloride, as well as sweat rate. This combined measurement approach reveals a negative correlation…
Citation impact
- FWCI
- 26.38
- Percentile
- 100%
- References
- 59
Authors
11- BZBowen ZhongCorresponding
Chinese Academy of Sciences, Institute of Semiconductors, University of Chinese Academy of Sciences
- XQXiaokun Qin
Chinese Academy of Sciences, Institute of Semiconductors, University of Chinese Academy of Sciences
- HXHao Xu
Chinese Academy of Sciences, Institute of Semiconductors, University of Chinese Academy of Sciences
- LLL Liu
Chinese Academy of Sciences, Institute of Semiconductors, University of Chinese Academy of Sciences
- LLLinlin Li
Chinese Academy of Sciences, Institute of Semiconductors, University of Chinese Academy of Sciences
Topics & keywords
- SWEAT
- Phenylalanine
- Amino acid
- Biochip
- Biochemistry
- Chemistry
- Biology
- Medicine