The ascorbate–glutathione cycle coming of age
University of Birmingham · University of Pretoria
Abstract
Concepts regarding the operation of the ascorbate-glutathione cycle and the associated water/water cycle in the processing of metabolically generated hydrogen peroxide and other forms of reactive oxygen species (ROS) are well established in the literature. However, our knowledge of the functions of these cycles and their component enzymes continues to grow and evolve. Recent insights include participation in the intrinsic environmental and developmental signalling pathways that regulate plant growth, development, and defence. In addition to ROS processing, the enzymes of the two cycles not only support the functions of ascorbate and glutathione, they also have 'moonlighting' functions. They are subject to…
Citation impact
- FWCI
- 101.21
- Percentile
- 100%
- References
- 243
Authors
2Topics & keywords
- Glutathione
- Reactive oxygen species
- Cell biology
- Biochemistry
- Signalling pathways
- Biology
- Signalling
- Interactome
- Clean water and sanitation