Superoxide dismutase and neurological disorders
JSS Academy of Higher Education and Research · American University of Antigua · +5 more institutions
Abstract
Superoxide dismutase (SOD) is a common antioxidant enzyme found majorly in living cells. The main physiological role of SOD is detoxification and maintain the redox balance, acts as a first line of defence against Reactive nitrogen species (RNS), Reactive oxygen species (ROS), and other such potentially hazardous molecules. SOD catalyses the conversion of superoxide anion free radicals (O 2 -. ) into molecular oxygen (O 2 ) and hydrogen peroxide (H 2 O 2 ) in the cells. Superoxide dismutases (SODs) are expressed in neurons and glial cells throughout the CNS both intracellularly and extracellularly. Endogenous oxidative stress (OS) linked with enlarged production of reactive oxygen metabolites (ROMs),…
Citation impact
- FWCI
- 25.71
- Percentile
- 100%
- References
- 320
Authors
8- SBSaravana Babu ChidambaramCorresponding
JSS Academy of Higher Education and Research
- NANikhilesh AnandCorresponding
American University of Antigua
- SVSudhir Varma
Ajman University, City University Ajman
- SRS Ramamurthy
University of Science and Technology, Ajman University, University of Science and Technology of Fujairah
- CVChandrasekaran Vichitra
JSS Academy of Higher Education and Research
Topics & keywords
- Superoxide dismutase
- Reactive oxygen species
- Superoxide
- Antioxidant
- Chemistry
- Enzyme
- Radical
- Biochemistry