articleInternational Journal of Molecular SciencesJan 23, 2024GOLD OA

Exploring the Potential of Bioactive Peptides: From Natural Sources to Therapeutics

Australian Research Council · Macquarie University · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Bioactive peptides, specific protein fragments with positive health effects, are gaining traction in drug development for advantages like enhanced penetration, low toxicity, and rapid clearance. This comprehensive review navigates the intricate landscape of peptide science, covering discovery to functional characterization. Beginning with a peptidomic exploration of natural sources, the review emphasizes the search for novel peptides. Extraction approaches, including enzymatic hydrolysis, microbial fermentation, and specialized methods for disulfide-linked peptides, are extensively covered. Mass spectrometric analysis techniques for data acquisition and identification, such as liquid chromatography, capillary…

Citation impact

126
total citations
FWCI
26.43
Percentile
100%
References
248
Citations per year

Authors

3

Topics & keywords

Keywords
  • In silico
  • Computational biology
  • Antimicrobial peptides
  • Context (archaeology)
  • Peptide
  • Chemistry
  • Biochemistry
  • Biology
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.

Funding