Exploring the Potential of Bioactive Peptides: From Natural Sources to Therapeutics
Australian Research Council · Macquarie University · +1 more institution
Abstract
Bioactive peptides, specific protein fragments with positive health effects, are gaining traction in drug development for advantages like enhanced penetration, low toxicity, and rapid clearance. This comprehensive review navigates the intricate landscape of peptide science, covering discovery to functional characterization. Beginning with a peptidomic exploration of natural sources, the review emphasizes the search for novel peptides. Extraction approaches, including enzymatic hydrolysis, microbial fermentation, and specialized methods for disulfide-linked peptides, are extensively covered. Mass spectrometric analysis techniques for data acquisition and identification, such as liquid chromatography, capillary…
Citation impact
- FWCI
- 26.43
- Percentile
- 100%
- References
- 248
Authors
3Topics & keywords
- In silico
- Computational biology
- Antimicrobial peptides
- Context (archaeology)
- Peptide
- Chemistry
- Biochemistry
- Biology
- Good health and well-being