Postoperative cognitive dysfunction—current research progress
University of Electronic Science and Technology of China · Sichuan Cancer Hospital
Abstract
Postoperative cognitive dysfunction (POCD) commonly occurs after surgery, particularly in elderly individuals. It is characterized by a notable decline in cognitive performance, encompassing memory, attention, coordination, orientation, verbal fluency, and executive function. This reduction in cognitive abilities contributes to extended hospital stays and heightened mortality. The prevalence of POCD can reach 40% within 1 week following cardiovascular surgery and remains as high as 17% 3 months post-surgery. Furthermore, POCD exacerbates the long-term risk of Alzheimer's disease (AD). As a result, numerous studies have been conducted to investigate the molecular mechanisms underlying POCD and potential…
Citation impact
- FWCI
- 39.94
- Percentile
- 100%
- References
- 108
Authors
4- QZQi Zhao
University of Electronic Science and Technology of China, Sichuan Cancer Hospital
- HWHui Wan
University of Electronic Science and Technology of China, Sichuan Cancer Hospital
- HPHui‐Lin PanCorresponding
University of Electronic Science and Technology of China, Sichuan Cancer Hospital
- YXYiquan XuCorresponding
University of Electronic Science and Technology of China, Sichuan Cancer Hospital
Topics & keywords
- Postoperative cognitive dysfunction
- Cognition
- Medicine
- Verbal fluency test
- Cognitive decline
- Disease
- Executive functions
- Psychology
- Good health and well-being