The Role of Obesity in Type 2 Diabetes Mellitus—An Overview

Obesity or excessive weight gain is identified as the most important and significant risk factor in the development and progression of type 2 diabetes mellitus (DM) in all age groups. It has reached pandemic dimensions, making the treatment of obesity crucial in the prevention and management of type 2 DM worldwide. Multiple clinical studies have demonstrated that moderate and sustained weight loss can improve blood glucose levels, insulin action and reduce the need for diabetic medications. A combined approach of diet, exercise and lifestyle modifications can successfully reduce obesity and subsequently ameliorate the ill effects and deadly complications of DM. This approach also helps largely in the…

• DF
  Deutsche Forschungsgemeinschaft

  Awards: WE 2554/17-1, WE2554/15-1, WE2554/13-1
• DK
  Deutsche Krebshilfe

  Awards: PTD 1-5, WE2554/13-1, WE2554/15-1, WE 2554/17-1, 70115581
• RA
  RWTH Aachen University

  Award: PTD 1-5