articleJAMA Network OpenFeb 9, 2024GOLD OA

Efficacy and Safety of 5-Day Oral Ensitrelvir for Patients With Mild to Moderate COVID-19

The University of Tokyo · National Center for Global Health and Medicine · +6 more institutions

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Abstract

Importance

Treatment options for COVID-19 are warranted irrespective of the presence of risk factors for severe disease.

Objective

To assess the efficacy and safety of ensitrelvir in patients with mild to moderate COVID-19. Design, Setting, and Participants: This phase 3 part of a phase 2/3, double-blind, placebo-controlled randomized clinical trial was conducted from February 10 to July 10, 2022, with a 28-day follow-up period, at 92 institutions in Japan, Vietnam, and South Korea. Patients (aged 12 to

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112
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38.96
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100%
References
33
Citations per year

Authors

13

Topics & keywords

Keywords
  • Medicine
  • Placebo
  • Randomized controlled trial
  • Clinical endpoint
  • Internal medicine
  • Population
  • Coronavirus disease 2019 (COVID-19)
  • Pediatrics
UN Sustainable Development Goals
  • Good health and well-being
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Funding