4D printed hydrogel scaffold with swelling-stiffening properties and programmable deformation for minimally invasive implantation
Hebei University of Technology · Chinese Academy of Sciences · +6 more institutions
Abstract
The power of three-dimensional printing in designing personalized scaffolds with precise dimensions and properties is well-known. However, minimally invasive implantation of complex scaffolds is still challenging. Here, we develop amphiphilic dynamic thermoset polyurethanes catering for multi-material four-dimensional printing to fabricate supportive scaffolds with body temperature-triggered shape memory and water-triggered programmable deformation. Shape memory effect enables the two-dimensional printed pattern to be fixed into temporary one-dimensional shape, facilitating transcatheter delivery. Upon implantation, the body temperature triggers shape recovery of the one-dimensional shape to its original…
Citation impact
- FWCI
- 31.91
- Percentile
- 100%
- References
- 45
Authors
14- BLBo LiuCorresponding
Hebei University of Technology, Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- HLHui Li
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- FMFengzhen Meng
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- ZXZiyang Xu
Tianjin University
- LHLiuzhi Hao
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, University of Chinese Academy of Sciences
Topics & keywords
- Materials science
- Shape-memory alloy
- Swelling
- Thermosetting polymer
- Morphing
- Stiffening
- Shape-memory polymer
- Scaffold
- Clean water and sanitation