reviewSmart MedicineFeb 1, 2024DIAMOND OA

Electrospun fiber‐based immune engineering in regenerative medicine

Shanghai Jiao Tong University · International Peace Maternity & Child Health Hospital · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Immune engineering, a burgeoning field within regenerative medicine, involves a spectrum of strategies to optimize the intricate interplay between tissue regenerative biomaterials and the host tissue. These strategies are applied across different types of biomaterials and various disease models, which encompasses finely modulating the immune response at the levels of immune cells and factors, aiming to mitigate adverse effects like fibrosis and persistent inflammation that may arise at the injury site and consequently promote tissue regeneration. With the continuous progress in electrospinning technology, the immunoregulatory capabilities of electrospun fibers have gained substantial attention over the years.…

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