reviewChemical Society ReviewsJan 1, 2024HYBRID OA

Biocatalysis: landmark discoveries and applications in chemical synthesis

University College Dublin · University of Manchester · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Biocatalysis has become an important tool in chemical synthesis, allowing access to complex molecules with high levels of activity and selectivity and with low environmental impact. Key discoveries in protein engineering, bioinformatics, recombinant technology and DNA sequencing have contributed towards the rapid acceleration of the field. This tutorial review explores enzyme engineering strategies and high-throughput screening approaches that have been applied for the discovery and development of enzymes for synthetic application. Landmark developments in the field are discussed and have been carefully selected to highlight the diverse synthetic applications of enzymes within the pharmaceutical, agricultural,…

Citation impact

127
total citations
FWCI
26.80
Percentile
100%
References
123
Citations per year

Authors

7

Topics & keywords

Keywords
  • Landmark
  • Biocatalysis
  • Biochemical engineering
  • Nanotechnology
  • Chemistry
  • Computer science
  • Engineering
  • Materials science
UN Sustainable Development Goals
  • Zero hunger
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