Self‐Healing, Injectable Hydrogel Dressing for Monitoring and Therapy of Diabetic Wound
Zhejiang A & F University · Wuhan University · +2 more institutions
Abstract
Abstract Chronic diabetic wound repair is a global medical challenge. Developing a hydrogel dressing to effectively promote angiogenesis and detect wound state in diabetic wound management is an unmet medical requirement. Herein, a facile and efficient strategy to prepare self‐healing hydrogel with enhanced angiogenesis and real‐time monitoring for diabetic wounds is presented, by cross‐linking carboxymethyl cellulose (CMC) with precoordinated europium‐ethylenediaminetetraacetic acid (Eu‐EDTA) complexes. Benefiting from the dynamic and reversible coordination interaction formation, the hydrogel exhibits remarkable injectability and self‐healing properties, thus forming efficient coverage in irregular and deep…
Citation impact
- FWCI
- 33.69
- Percentile
- 100%
- References
- 41
Authors
6Topics & keywords
- Angiogenesis
- Wound healing
- Granulation tissue
- Materials science
- Matrix metalloproteinase
- Chronic wound
- Biomedical engineering
- In vivo