CAR T therapies in multiple myeloma: unleashing the future
Qom University of Medical Science and Health Services · Shahid Sadoughi University of Medical Sciences and Health Services · +9 more institutions
Abstract
In recent years, the field of cancer treatment has witnessed remarkable breakthroughs that have revolutionized the landscape of care for cancer patients. While traditional pillars such as surgery, chemotherapy, and radiation therapy have long been available, a cutting-edge therapeutic approach called CAR T-cell therapy has emerged as a game-changer in treating multiple myeloma (MM). This novel treatment method complements options like autologous stem cell transplants and immunomodulatory medications, such as proteasome inhibitors, by utilizing protein complexes or anti-CD38 antibodies with potent complement-dependent cytotoxic effects. Despite the challenges and obstacles associated with these treatments, the…
Citation impact
- FWCI
- 35.10
- Percentile
- 100%
- References
- 138
Authors
10- MSMohsen Sheykhhasan
Qom University of Medical Science and Health Services
- AAAmirhossein Ahmadieh-Yazdi
Shahid Sadoughi University of Medical Sciences and Health Services, Qom University of Medical Science and Health Services
- RVRosario Vicidomini
National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development
- NPNaresh Poondla
Icahn School of Medicine at Mount Sinai
- HTHamid Tanzadehpanah
Mashhad University of Medical Sciences
Topics & keywords
- Medicine
- Context (archaeology)
- Multiple myeloma
- Bortezomib
- Clinical trial
- Cancer research
- Immunology
- Internal medicine
- Good health and well-being