articleExperimental & Molecular MedicineMar 5, 2024GOLD OA

Advances in single-cell omics and multiomics for high-resolution molecular profiling

University of Seoul · Soongsil University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Single-cell omics technologies have revolutionized molecular profiling by providing high-resolution insights into cellular heterogeneity and complexity. Traditional bulk omics approaches average signals from heterogeneous cell populations, thereby obscuring important cellular nuances. Single-cell omics studies enable the analysis of individual cells and reveal diverse cell types, dynamic cellular states, and rare cell populations. These techniques offer unprecedented resolution and sensitivity, enabling researchers to unravel the molecular landscape of individual cells. Furthermore, the integration of multimodal omics data within a single cell provides a comprehensive and holistic view of cellular processes.…

Citation impact

143
total citations
FWCI
30.00
Percentile
100%
References
100
Citations per year

Authors

6

Topics & keywords

Keywords
  • Omics
  • Profiling (computer programming)
  • Computational biology
  • Systems biology
  • Biology
  • Computer science
  • Bioinformatics
No related works found for this paper.

Funding