Degradable biomedical elastomers: paving the future of tissue repair and regenerative medicine

Degradable biomedical elastomers (DBE), characterized by controlled biodegradability, excellent biocompatibility, tailored elasticity, and favorable network design and processability, have become indispensable in tissue repair. This review critically examines the recent advances of biodegradable elastomers for tissue repair, focusing mainly on degradation mechanisms and evaluation, synthesis and crosslinking methods, microstructure design, processing techniques, and tissue repair applications. The review explores the material composition and cross-linking methods of elastomers used in tissue repair, addressing chemistry-related challenges and structural design considerations. In addition, this review focuses…

• NN
  National Natural Science Foundation of China

  Awards: 52003216, 12141203, 82272155, 52273149
• NP
  Northwestern Polytechnical University

  Award: CX202308
• CP
  China Postdoctoral Science Foundation

  Awards: 2022M712506), 2021M693007
• NS
  Natural Science Foundation of Shaanxi Province

  Awards: 2020JQ-122, 2024RS-CXTD-29
• NK
  National Key Research and Development Program of China

  Award: 2023YFB4605800
• KR
  Key Research and Development Projects of Shaanxi Province

  Award: 2023-YBSF-150
• BA
  Basic and Applied Basic Research Foundation of Guangdong Province

  Award: 22201910240001410