Co-selection for antibiotic resistance by environmental contaminants

The environment is increasingly recognised as a hotspot for the selection and dissemination of antibiotic resistant bacteria and antibiotic resistance genes. These can be selected for by antibiotics and non-antibiotic agents (such as metals and biocides), with the evidence to support this well established by observational and experimental studies. However, there is emerging evidence to suggest that plant protection products (such as herbicides), and non-antibiotic drugs (such as chemotherapeutic agents), can also co-select for antibiotic resistance. This review aims to provide an overview of four classes of non-antibiotic agents (metals, biocides, plant protection products, and non-antibiotic drugs) and how…

• A
  AstraZeneca
• SR
  Sight Research UK

  Awards: NE/R01373X/1, NE/S006257/1
• BA
  Biotechnology and Biological Sciences Research Council

  Award: BB/T508330/1
• NE
  Natural Environment Research Council

  Awards: NE/R01373X/1, NE/R01373X/, NE/R01373X/1, NE/R011524/1, NE/S006257/1, NE/S006257/1