Recent advances in extracellular vesicles for therapeutic cargo delivery
Beth Israel Deaconess Medical Center · Harvard University · +5 more institutions
Abstract
Exosomes, which are nanosized vesicles secreted by cells, are attracting increasing interest in the field of biomedical research due to their unique properties, including biocompatibility, cargo loading capacity, and deep tissue penetration. They serve as natural signaling agents in intercellular communication, and their inherent ability to carry proteins, lipids, and nucleic acids endows them with remarkable therapeutic potential. Thus, exosomes can be exploited for diverse therapeutic applications, including chemotherapy, gene therapy, and photothermal therapy. Moreover, their capacity for homotypic targeting and self-recognition provides opportunities for personalized medicine. Despite their advantages as…
Citation impact
- FWCI
- 75.90
- Percentile
- 100%
- References
- 120
Authors
6- HIHyo In KimCorresponding
Beth Israel Deaconess Medical Center, Harvard University
- JBJin Bong Park
Kyung Hee University
- YZYin Zhu
University of Georgia, Charlie Norwood VA Medical Center
- XWXiaoyun Wang
University of Georgia, Charlie Norwood VA Medical Center
- YHYohan Han
University of Georgia, Charlie Norwood VA Medical Center, Wonkwang University
Topics & keywords
- Microvesicles
- Exosome
- Drug delivery
- Extracellular vesicles
- Nanotechnology
- microRNA
- Computer science
- Computational biology
Funding
- NRNational Research Foundation
- KHKorea Health Industry Development InstituteAward: HF23C0120
- NRNational Research Foundation of KoreaAwards: 2021R1A5A8029876, RS-2023-00213024
- MOMinistry of Science and ICT, South KoreaAwards: 2021R1A5A8029876, RS-2023-00213024
- NHNational Heart, Lung, and Blood InstituteAward: R00HL141685