SERS-based microdevices for use as in vitro diagnostic biosensors
Chung-Ang University · Binzhou Medical University · +3 more institutions
Abstract
Diagnostic methods, such as fluorescence and chemiluminescence, owing to its high sensitivity and multiplex detection capability. However, for the implementation of SERS detection technology in disease diagnosis, a SERS-based assay platform capable of analyzing clinical samples is essential. Moreover, infectious diseases like COVID-19 require the development of point-of-care (POC) diagnostic technologies that can rapidly and accurately determine infection status. As an effective assay platform, SERS-based bioassays utilize SERS nanotags labeled with protein or DNA receptors on Au or Ag nanoparticles, serving as highly sensitive optical probes. Additionally, a microdevice is necessary as an interface between…
Citation impact
- FWCI
- 29.62
- Percentile
- 100%
- References
- 361
Authors
12Topics & keywords
- Biosensor
- Nanotechnology
- In vitro
- Chemistry
- Biochemical engineering
- Materials science
- Engineering
- Biochemistry